• First-of-Its-Kind Study Reveals How Stem Cell Proteins Restore Aging Tissues

    Is there a way to turn back the clock on aging? Mitra Lavasani, PhD, director of the Translational Cell Therapy Lab at Shirley Ryan 暴走黑料 is working with her team to find out.
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    “Mini Brains” Can Advance Understanding of Brain

    A recent study in the journal Nature Biomedical Engineering highlighted a new technology that can allow for a better understanding of brain development and disease.
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    What are Organoids?

    Dr. Colin Franz is developing organoids — artificially grown masses of cells or tissue that resemble organs — to see whether this technique can contribute to life-changing discoveries for our patients.
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    Speeding Drug Repurposing for Patients

    Using an Anti-Cancer Drug to Treat Muscle Contractures in Cerebral Palsy.
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    Our Projects

    Take a look at a few of the projects we work on everyday.

    Stimulus-Response on Select Serum Biomarkers in Knee Osteoarthritis

    Research Project

    Muscle Impairment in Children with Cerebral Palsy: a Role for Muscle Stem Cell Dysfunction and Drug Repurposing
    PROJECT TYPE: Cerebral Palsy, Muscle, Biology, Muscle Fibers, Cell Biology, Stem Cells, Cell Culture

    Research Project

    Defining trajectories of linguistic, cognitive-communicative and quality of life outcomes in aphasia
    PROJECT TYPE: Stroke, Aphasia, Quality Improvement, Outcomes, Brain, Biology, Speech Disorders

    Research Project

    Sarcomere Measurements
    PROJECT TYPE: Muscle Fibers, Muscle, Cerebral Palsy, Muscular Dystrophy, Physiology

    Research Project

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    Selected Publications

    Does Time Tick Faster in Cerebral Palsy? Accelerated Aging as a Framework for Skeletal Muscle Dysfunction.

    Cerebral palsy (CP) is the most common cause of childhood-onset physical disability. It results from injury to the developing brain and is characterized by motor impairments, muscle weakness, and fatigue. CP is commonly associated with marked deficits in muscle mass and function, and many individuals experience early declines in physical performance and functional ability as they age. These features resemble changes observed in age-related muscle loss, that is, sarcopenia, raising the…

    Human spinal cord organoids: A powerful tool to redefine gray matter and lower motor neuron pathophysiology in spinal cord injury.

    Macrophages, muscle stem cells, and repair; immunohistochemical characteristics in muscle growth impairments in children with cerebral palsy.

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    Interested in joining us?

    Contact Our Lab